Ludolf Von Krehl
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Albrecht Ludolf von Krehl (December 26, 1861 – May 26, 1937) was a German internist and physiologist who was a native of
Leipzig Leipzig ( , ; Upper Saxon: ) is the most populous city in the German state of Saxony. Leipzig's population of 605,407 inhabitants (1.1 million in the larger urban zone) as of 2021 places the city as Germany's eighth most populous, as ...
. He was the son of Orientalist
Christoph Krehl Christoph Ludolf Ehrenfried Krehl (29 June 1825 – 15 May 1901, Leipzig) was a German orientalist born in Meissen. Biography From 1843 Krehl studied theology and philology at the University of Leipzig, where he attended lectures by Heinric ...
(1825–1901) He studied at the Universities of
Heidelberg Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914 ...
and
Leipzig Leipzig ( , ; Upper Saxon: ) is the most populous city in the German state of Saxony. Leipzig's population of 605,407 inhabitants (1.1 million in the larger urban zone) as of 2021 places the city as Germany's eighth most populous, as ...
, and later was an assistant to
Ernst Leberecht Wagner Ernst Leberecht Wagner (12 March 1829 – 10 February 1888) was a German pathologist who was a native of Dehlitz, a town in the Burgenlandkreis district of Saxony-Anhalt. Education and Career He studied medicine in Leipzig under Karl Augu ...
(1829–1888) and Heinrich Curschmann (1846–1910) at the medical clinic in Leipzig. In 1888 he obtained his habilitation, becoming head of the medical clinic at
Jena Jena () is a German city and the second largest city in Thuringia. Together with the nearby cities of Erfurt and Weimar, it forms the central metropolitan area of Thuringia with approximately 500,000 inhabitants, while the city itself has a po ...
in 1892. In 1899 he became director of the clinic at the
University of Marburg The Philipps University of Marburg (german: Philipps-Universität Marburg) was founded in 1527 by Philip I, Landgrave of Hesse, which makes it one of Germany's oldest universities and the oldest still operating Protestant university in the wor ...
, and soon afterwards served as professor of special pathology and therapy of internal diseases in
Greifswald Greifswald (), officially the University and Hanseatic City of Greifswald (german: Universitäts- und Hansestadt Greifswald, Low German: ''Griepswoold'') is the fourth-largest city in the German state of Mecklenburg-Western Pomerania after Rosto ...
(1900–02). From 1902 to 1904 he was a professor at the
University of Tübingen The University of Tübingen, officially the Eberhard Karl University of Tübingen (german: Eberhard Karls Universität Tübingen; la, Universitas Eberhardina Carolina), is a public research university located in the city of Tübingen, Baden-W ...
, and in 1904 he succeeded
Bernhard Naunyn Bernhard Naunyn (2 September 1839 – 26 July 1925) was German pathologist born in Berlin. Biography After receiving his degree at the University of Berlin in 1863, he became an assistant to pathologist Friedrich Theodor von Frerichs (1819–1 ...
(1839–1925) at the
University of Strasbourg The University of Strasbourg (french: Université de Strasbourg, Unistra) is a public research university located in Strasbourg, Alsace, France, with over 52,000 students and 3,300 researchers. The French university traces its history to the ea ...
. While at Strasbourg, he provided the necessary facilities to
Albert Fraenkel Julius Albert Fraenkel (3 June 1864 – 22 December 1938) was a German physician who helped establish ''Streptococcus pneumoniae'' as a cause of bacterial pneumonia and championed intravenous ouabain for use in heart failure. The ''Albert-Fraenke ...
(1864–1938) for the latter's testing of intravenous
strophanthin Strophanthins are cardiac glycosides in plants of the genus ''Strophanthus''. The singular may refer to: * g-Strophanthin, also known as ouabain * k-Strophanthin It is commonly used in euthanasia (lethal injections) See also

* Cardenolide {{C ...
. From 1907 until 1932 he was a professor and director of the medical clinic at the University of
Heidelberg Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914 ...
. One of his better known assistants at
Heidelberg Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914 ...
was Viktor von Weizsäcker (1886–1957). Krehl made contributions in the field of
cardiac pathology The heart is a muscular organ in most animals. This organ pumps blood through the blood vessels of the circulatory system. The pumped blood carries oxygen and nutrients to the body, while carrying metabolic waste such as carbon dioxide to t ...
and in his research of metabolic diseases. Also, he admired the
psychoanalytic PsychoanalysisFrom Greek: + . is a set of theories and therapeutic techniques"What is psychoanalysis? Of course, one is supposed to answer that it is many things — a theory, a research method, a therapy, a body of knowledge. In what might ...
work of
Sigmund Freud Sigmund Freud ( , ; born Sigismund Schlomo Freud; 6 May 1856 – 23 September 1939) was an Austrian neurologist and the founder of psychoanalysis, a clinical method for evaluating and treating pathologies explained as originating in conflicts ...
and
Josef Breuer Josef Breuer ( , ; 15 January 1842 – 20 June 1925) was a distinguished physician who made key discoveries in neurophysiology, and whose work in the 1880s with his patient Bertha Pappenheim, known as Anna O., developed the talking cure (cathar ...
, and had a keen interest in
psychopathological Psychopathology is the study of abnormal cognition, behaviour, and experiences which differs according to social norms and rests upon a number of constructs that are deemed to be the social norm at any particular era. Biological psychopathol ...
aspects of disease from an individualized, psychosomatic standpoint. Among his written works was a landmark textbook on
pathological Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in th ...
physiology that laid a scientific basis for
clinical medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practice ...
. This textbook was first published in 1893 as ''Grundriß der allgemeinen klinischen Pathologie'' (Later known as ''Pathologische Physiologie''), and eventually ran to fourteen editions. Krehl was a catalyst behind the founding of the " Kaiser Wilhelm Institute for Medical Research", which today is known as the
Max Planck Institute for Medical Research The Max Planck Institute for Medical Research in Heidelberg, Germany, is a facility of the Max Planck Society for basic medical research. Since its foundation, six Nobel Prize laureates worked at the Institute: Otto Fritz Meyerhof (Physiology), R ...
in Heidelberg.Frankonia Heidelberg
(biography translated from German)


Selected writings

* ''Grundriß der allgemeinen klinischen Pathologie'', (Fundamentals of General Clinical Pathology), later known as ''Pathologische Physiologie'' (Pathological Physiology); Leipzig (1893) * ''Die Erkrankungen des Herzmuskels'', In:
Carl Nothnagel Carl Wilhelm Hermann Nothnagel (28 September 1841 – 7 July 1905) was a German internist born in Alt-Lietzegöricke ( pl, Stare Łysogórki), near Bärwalde in der Neumark ( pl, Mieszkowice), Neumark, Brandenburg. Career The son of a pha ...
's: Experimentelle Pathologie und Therapie, Bd. 15/1, Holder, Wien (1901) * ''Krankheitsform und Persönlichkeit'', Thieme, Leipzig (1929) * ''Über die Naturheilkunde'' (1935)


References


Deutsche Biographie
(translated biography) * "This article incorporates information based on a translation of an equivalent article at the German Wikipedia". *


External links

* * {{DEFAULTSORT:Krehl, Ludolf von 1861 births 1937 deaths German physiologists Physicians from Leipzig Heidelberg University faculty University of Tübingen faculty University of Marburg faculty University of Greifswald faculty University of Jena faculty University of Strasbourg faculty Recipients of the Pour le Mérite (civil class) Max Planck Institute directors